![]() The patient however, should be advised to take a Point of Care antigen or NAAT test for SARS-CoV-2, when and where available, and follow local/regional public health authority recommendations for cases and contacts. Testing may either not be available, or accurate, early in the course of illness. With Omicron, clinical presumptive diagnosis should be considered with symptoms compatible with COVID-19 and a history of contact with known case(s). When fever occurred in Omicron cases, it was more frequently reported in unvaccinated than in vaccinated cases.Īs new variants emerge and more of the population becomes vaccinated, there will be ongoing changes in the patterns of symptoms that individuals experience. This response is different than the predominant symptoms earlier in the pandemic, which included fever, cough, chills and muscle pain. ![]() During the Omicron wave that began in November 2021, those who have had at least 2 vaccinations reported milder symptoms typical symptoms reported during the Omicron wave included runny nose, headache, sneezing, and sore throat. This study found that symptom frequency and severity has varied by circulating variant and by vaccination status. The ZOE COVID Study from the United Kingdom is a comprehensive system that tracks COVID-19 symptoms. To date, there remains no comprehensive list of symptoms that has been validated to have high specificity or sensitivity for COVID-19. Symptoms that are absent at the onset of illness may develop over time with disease progression. Published reports often over-represent individuals who have more severe symptoms, and these may differ across care settings and between different age groups and vaccine statuses. ![]() Disease severity and risk factors for severe diseaseĬOVID-19 includes clinical features that present in varying ways with respect to frequency and severity and vary by age, vaccination status and variants of concern.This document is intended to provide clinicians with interim information on currently known clinical features of COVID-19, including signs and symptoms, incubation period, disease severity and risk factors for severe disease and SARS-CoV-2 variants of concern. The information below is based on currently available scientific evidence and informed by expert clinician opinion, and is subject to change as new information becomes available.
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